Latha Satish

Latha Satish MS M Phil Ph D

Research Assistant Professor

las238@pitt.edu

Education:

B. S., University of Madras, India

M. S., University of Madras, India

M.Phil., University of Madras, India

Ph D University of Madras, India

Post-Doctoral Fellow, Department of Pathology, University of Pittsburgh, USA

Research Interests:

Skin Wound healing, Burn wounds, Skin Fibrosis, Palmar Fascia Fibrosis (Dupuytren’s Contracture)

Publications:

1. Mechanical effects, antimicrobial efficacy and cytotoxicity of usnic acid as a biofilm prophylaxis in PMMA.  Kim S, Greenleaf R, Miller MC, Satish L, Kathju S, Ehrlich G, Christopher Post J, Sotereanos NG, Stoodley P. J Mater Sci Mater Med. 2011 Sep 22. [Epub ahead of print]

2. Chaperonin containing T-complex polypeptide (CCT) subunit expression in oral mucosal wounds and fibroblasts. Satish L, Lo N, Gallo PH, Johnson S, Haberman S, Kathju S. Cell Stress Chaperones. 2011 Nov;16(6):675-80. Epub 2011 Jun 28.

3. Increased expression of Ero1L-alpha in healing fetal wounds.Gallo PH, Satish L, Johnson S, Kathju S. BMC Res Notes. 2011 Jun 6;4:175.

4. Reversal of TGF-β1 stimulation of α-smooth muscle actin and extracellular matrix components by cyclic AMP in Dupuytren’s-derived fibroblasts. Satish L, Gallo PH, Baratz ME, Johnson S, Kathju S. BMC Musculoskelet Disord. 2011 May 25;12:113.

5. Cellular and Molecular Characteristics of Scarless versus Fibrotic Wound Healing. Satish L, Kathju S. Dermatol Res Pract. 2010;2010:790234. Epub 2010 Dec 27.

6. Multiple displacement amplification as an adjunct to PCR-based detection of Staphylococcus aureus in synovial fluid. Kathju S, Lasken RS, Satish L, Johnson S, Stoodley P, Post JC, Ehrlich GD. BMC Res Notes. 2010 Oct 13;3:259.

7. Chaperonin containing T-complex polypeptide subunit eta (CCT-eta) is a specific regulator of fibroblast motility and contractility. Satish L, Johnson S, Wang JH, Post JC, Ehrlich GD, Kathju S. PLoS One. 2010 Apr 30;5(4):e10063.

8. Cloning and expression of rabbit CCT subunits eta and beta in healing cutaneous wounds. Satish L, Johnson S, Abdulally A, Post JC, Ehrlich GD, Kathju S. Cell Stress Chaperones. 2010 Nov;15(6):819-26.

9. Expression of receptor for activated C kinase 1 in healing skin and mucosal wounds. Satish L, Hogg J, Johnson S, Oswald D, Post JC, Ehrlich GD, Kathju S. Ann Plast Surg. 2010 Feb;64(2):238-41.

10. Periostin differentially induces proliferation, contraction and apoptosis of primary Dupuytren’s disease and adjacent palmar fascia cells. Vi L, Feng L, Zhu RD, Wu Y, Satish L, Gan BS, O’Gorman DB. Exp Cell Res. 2009 Dec 10;315(20):3574-86. Epub 2009 Jul 18.

11. Differential expression of chaperonin containing T-complex polypeptide (CCT) subunits during fetal and adult skin wound healing. Satish L, Abdulally A, Oswald D, Johnson S, Hu FZ, Post JC, Ehrlich GD, Kathju S. Cell Stress Chaperones. 2008 Dec;13(4):527-33. Epub 2008 May 9.

12. Identification of differentially expressed genes in fibroblasts derived from patients with Dupuytren’s Contracture. Satish L, LaFramboise WA, O’Gorman DB, Johnson S, Janto B, Gan BS, Baratz ME, Hu FZ, Post JC, Ehrlich GD, Kathju S. BMC Med Genomics. 2008 Apr 23;1:10.

13. Identification of differentially expressed genes in scarless wound healing utilizing polymerase chain reaction-suppression subtractive hybridization. Kathju S, Satish L, Rabik C, Rupert T, Oswald D, Johnson S, Hu FZ, Post JC, Ehrlich GD. Wound Repair Regen. 2006 Jul-Aug;14(4):413-20.

14. Gene expression patterns in isolated keloid fibroblasts. Satish L, Lyons-Weiler J, Hebda PA, Wells A.Wound Repair Regen. 2006 Jul-Aug;14(4):463-70.

15. Interferon-inducible protein 9 (CXCL11)-induced cell motility in keratinocytes requires calcium flux-dependent activation of mu-calpain. Satish L, Blair HC, Glading A, Wells A. Mol Cell Biol. 2005 Mar;25(5):1922-41.

16. Keloid fibroblast responsiveness to epidermal growth factor and activation of downstream intracellular signaling pathways. Satish L, Babu M, Tran KT, Hebda PA, Wells A. Wound Repair Regen. 2004 Mar-Apr;12(2):183-92.

17. Epidermal growth factor activates m-calpain (calpain II), at least in part, by extracellular signal-regulated kinase-mediated phosphorylation. Glading A, Bodnar RJ, Reynolds IJ, Shiraha H, Satish L, Potter DA, Blair HC, Wells A. Mol Cell Biol. 2004 Mar;24(6):2499-512.

18. Aging-related attenuation of EGF receptor signaling is mediated in part by increased protein tyrosine phosphatase activity. Tran KT, Rusu SD, Satish L, Wells A. Exp Cell Res. 2003 Oct 1;289(2):359-67.

19. Glu-Leu-Arg-negative CXC chemokine interferon gamma inducible protein-9 as a mediator of epidermal-dermal communication during wound repair. Satish L, Yager D, Wells A. J Invest Dermatol. 2003 Jun;120(6):1110-7.

20. The involvement of free radicals in burn injury: a review. Latha B, Babu M. Burns. 2001 Jun;27(4):309-17. Review. No abstract available.

21. Physicochemical properties of extracellular matrix proteins in post-burn human granulation tissue. Latha B, Ramakrishnan M, Jayaraman V, Babu M. Comp Biochem Physiol B Biochem Mol Biol. 1999 Nov;124(3):241-9.

22. The efficacy of trypsin: chymotrypsin preparation in the reduction of oxidative damage during burn injury. Latha B, Ramakrishnan M, Jayaraman V, Babu M. Burns. 1998 Sep;24(6):532-8. Erratum in: Burns 1999 Mar;25(2):192.

23. Serum enzymatic changes modulated using trypsin: chymotrypsin preparation during burn wounds in humans. Latha B, Ramakrishnan M, Jayaraman V, Babu M. Burns. 1997 Nov-Dec;23(7-8):560-4.

24. Action of trypsin:chymotrypsin (Chymoral forte DS) preparation on acute-phase proteins following burn injury in humans. Latha B, Ramakrishnan KM, Jayaraman V, Babu M. Burns. 1997 Mar;23 Suppl 1:S3-7.

 

Personal Interests: Music, Movies, My Pets.

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